Outcome | Radiologists’ BI-RADS category (0, 3, 4, 5) | Standalone AI (Cutoff 10%) | P value | ||
---|---|---|---|---|---|
Estimate | 95% CI | Estimate | 95% CI | ||
Non-dense | Â | Â | Â | Â | Â |
CDR, per 1000 examinations | 1.2 | 0.7–2.0 | 1.2 | 0.7–2.0 | 1.000 |
Sensitivity, % | 77.8 | 52.4–93.6 | 77.8 | 52.4–93.6 | 1.000 |
Specificity, % | 86.5 | 85.9–87.1 | 96.1 | 95.8–96.5 | < 0.001 |
PPV, % | 0.9 | 0.5–1.5 | 3.0 | 1.7–5.1 | < 0.001 |
Recall rate, % | 13.6 | 13.0–14.2 | 4.0 | 3.6–4.4 | < 0.001 |
AUC | 0.82 | 0.72–0.92 | 0.87 | 0.77–0.97 | 0.234 |
Heterogeneously dense | Â | Â | Â | Â | Â |
CDR, per 1000 examinations | 1.2 | 0.9–1.6 | 1.0 | 0.8–1.4 | 0.059 |
Sensitivity, % | 75.8 | 63.6–85.5 | 63.6 | 50.9–75.1 | 0.059 |
Specificity, % | 77.9 | 77.5–78.3 | 93.6 | 93.4–93.8 | < 0.001 |
PPV, % | 0.6 | 0.4–0.7 | 1.6 | 1.1–2.1 | < 0.001 |
Recall rate, % | 22.2 | 21.8–22.6 | 6.5 | 6.3–6.7 | < 0.001 |
AUC | 0.77 | 0.72–0.82 | 0.79 | 0.73–0.85 | 0.575 |
Extremely dense | Â | Â | Â | Â | Â |
CDR, per 1000 examinations | 1.0 | 0.7–1.3 | 1.1 | 1.1–1.5 | 0.346 |
Sensitivity, % | 61.0 | 47.4–73.5 | 67.8 | 54.4–79.4 | 0.346 |
Specificity, % | 74.5 | 74.1–75.0 | 91.5 | 91.2–91.7 | < 0.001 |
PPV, % | 0.4 | 0.3–0.5 | 1.2 | 0.9–1.7 | < 0.001 |
Recall rate, % | 25.5 | 25.1–26.0 | 8.6 | 8.4–8.9 | < 0.001 |
AUC | 0.68 | 0.62–0.74 | 0.80 | 0.74–0.86 | 0.297 |