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Fig. 7 | Breast Cancer Research

Fig. 7

From: Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer

Fig. 7

Identification of differentially expressed genes (DEGs) between non-pCR and pCR group and functional enrichment analysis for these DEGs. (A) Differential gene volcano plot (genes with q-value < 0.05 and |log2 fold change (FC)|>1 were considered as significant, red and blue dots indicate up- and down-regulated genes, respectively). (B) Cluster analysis of DEGs between non-pCR and pCR group. Each column represents a subject and each row represents a gene. (C) KEGG enrichment analysis of DEGs at level 1 and level 2. (D) Sankey dot plot for level 3 KEGG enrichment analysis of DEGs. (E) GO classification analysis of DEGs (top 30)

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Breast Cancer Research

ISSN: 1465-542X

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