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Fig. 6 | Breast Cancer Research

Fig. 6

From: Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer

Fig. 6

Dynamic alteration profile of metabolites in non-pCR and pCR patients basing on the total DEMs (102) in non-pCR and pCR patients. (A) Time trend cluster summary of serum metabolites in non-pCR group. (B) Time trend cluster summary of the serum metabolites in pCR group. Yellow or green lines represent metabolites with low membership values, whereas red and purple lines represent metabolites with high membership values. (C-G) Relative expression intensity of five metabolites that exhibited the same change trend over time in the same group. Each value of the metabolite is the mean of samples in every group at different time point. T1, the time point at baseline of neoadjuvant treatment. T2, the time point after 2 cycles of neoadjuvant treatment. T3, the time point after 6 cycles (before surgery) of neoadjuvant treatment

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Breast Cancer Research

ISSN: 1465-542X

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