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Fig. 4 | Breast Cancer Research

Fig. 4

From: Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer

Fig. 4

Comprehensive analyses of four pre-therapeutic metabolites performed via random forest analysis. (A) Receiver operating characteristic curve analysis of the efficacy of the four metabolites-based predictive model. 1: Sophorose; 2: Sophorose + ADA; 3. Sophorose + ADA + Taurine; 4: Sophorose + ADA + Taurine + 6-hydroxy-2-aminohexanoic acid; (B) Violin plots depicting the levels of four pre-therapeutic metabolites between non-PCR and PCR patients. (C) Violin plots depicting the levels of four pre-therapeutic metabolites among patients with different MP scores. (D) Spearman correlation of the four pre-therapeutic metabolites with MP grade

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