Skip to main content
Fig. 3 | Breast Cancer Research

Fig. 3

From: Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2 + breast cancer

Fig. 3

Metabolite pathway analysis using KEGG basing on pre-therapeutic DEMs. (A) Pre-therapeutic metabolic pathway enrichment of 100 differential metabolites between non-pCR patients and pCR patients at baseline of neoadjuvant therapy. The P-value of the red dashed line was 0.01 and that of the blue dashed line was 0.05. (B) Bubble plot depicting the KEGG pathways (top 20) in which 46 elevated metabolites were substantially enriched (P < 0.05); (C) Bubble plot depicting the KEGG pathways (top 20) in which 54 downregulated metabolites were substantially enriched (P < 0.05)

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us