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Fig. 6 | Breast Cancer Research

Fig. 6

From: Augmented interpretation of HER2, ER, and PR in breast cancer by artificial intelligence analyzer: enhancing interobserver agreement through a reader study of 201 cases

Fig. 6

A Carcinoma in situ areas containing HER2 (human epidermal growth factor receptor 2)-stained cells were classified as cancer area (CA) by HER2 analyzer (bar: 200 μm). B ER (estrogen receptor)/PR (progesterone receptor) analyzer recognized the inked area at the margin of the tissue as a CA with ER-positive tumor cells (bar left: 5 mm, right: 200 μm). C ER/PR analyzer barely caught the CA through the entire area of PR-stained slide (bar left: 5 mm, right: 100 μm). D In a PR-stained slide, pathologists focused the visible clusters of positive tumor cells at low magnification and classified them as low positive all together even after revision. In contrast, ER/PR analyzer counted all the tumor cells and interpreted them as negative (bar left: 5 mm, right: 100 μm)

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Breast Cancer Research

ISSN: 1465-542X

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