Table 5 Diagnostic performance of ultrasound and contrast-enhanced ultrasound based on BI-RADS category 4B threshold
From: Contrast-enhanced ultrasound to predict malignant upgrading of atypical ductal hyperplasia
Variable | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
All | ||||
US | 79.2 (42/53) | 73.7 (42/57) | 73.7 (42/57) | 79.2 (42/53) |
US + CEUS | 96.2 (51/53) | 66.7 (38/57) | 72.9 (51/70) | 95.0 (38/40) |
P value | 0.012 | 0.289 | 0.917 | 0.030 |
> 2 cm | ||||
US | 82.6 (19/23) | 83.3 (5/6) | 95.0 (19/20) | 55.6 (5/9) |
US + CEUS | 95.7 (22/23) | 83.3 (5/6) | 95.7 (22/23) | 83.3 (5/6) |
P value | 0.375 | > 0.99 | 0.919 | 0.580 |
≤ 2 cm | ||||
US | 76.7 (23/30) | 72.5 (37/51) | 62.2 (23/37) | 84.1 (37/44) |
US + CEUS | 96.7 (29/30) | 64.7 (33/51) | 61.7 (29/47) | 97.1 (33/34) |
P value | 0.031 | 0.289 | 0.966 | 0.135 |