Table 4 Diagnostic performance of ultrasound and contrast-enhanced ultrasound based on BI-RADS category 4A threshold
From: Contrast-enhanced ultrasound to predict malignant upgrading of atypical ductal hyperplasia
Variable | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
All | ||||
US | 100 (53/53) | 14.0 (8/57) | 52.0 (53/102) | 100 (8/8) |
US + CEUS | 100 (53/53) | 29.8 (17/57) | 57.0 (53/93) | 100 (17/17) |
P value | – | 0.022 | 0.481 | – |
> 2 cm | ||||
US | 100 (23/23) | 16.7 (1/6) | 82.1 (23/28) | 100 (1/1) |
US + CEUS | 100 (23/23) | 16.7 (1/6) | 82.1 (23/28) | 100 (1/1) |
P value | – | > 0.99 | > 0.99 | – |
≤ 2 cm | ||||
US | 100 (30/30) | 13.7 (7/51) | 40.5 (30/74) | 100 (7/7) |
US + CEUS | 100 (30/30) | 31.4 (16/51) | 46.2 (30/65) | 100 (16/16) |
P value | – | 0.012 | 0.505 | – |