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Fig. 5 | Breast Cancer Research

Fig. 5

From: Identification of a Notch transcriptomic signature for breast cancer

Fig. 5

The signature score for the 20-gene signature in different subtypes of breast cancer. A Analysis of signature scores at the ground state in basal-like, HER2 and Luminal A (LumA) cell lines from the 19-cell line transcriptomic dataset. B Analysis of the relative signature score in the 19-cell line dataset under “Notch on” and “Notch off” conditions, as indicated. C The relative signature score changes under “Notch on” (blue) and “Notch off” (orange) conditions. D Analysis of signature scores for the 20-gene signature in basal-like/TNBC (Basal), HER2, Luminal A (LumA) and Luminal B (LumB) breast cancer, in the TCGA, METABRIC and Oslo2 datasets, as indicated. (*p < 0.05; **p < 0.001; ***p < 0.0001 and ****p < 0.00001)

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