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Table 5 Joint effects of AL and breast cancer risk factors

From: Association between allostatic load and breast cancer risk: a cohort study

 

AL low

AL high

Age group *

  

 < 57 years old

Reference

1.08 (0.99, 1.18)

 ≥ 57 years old

1.24 (1.13, 1.38)

1.54 (1.40, 1.70)1

Family history of breast cancer

  

 No

Reference

1.15 (1.07, 1.24)

 Yes

1.35 (1.17, 1.56)

1.81 (1.57, 2.09)

PRS

  

 < 75%

Reference

1.14 (1.06, 1.23)

 ≥ 75%

2.35 (2.18, 2.54)

2.87 (2.66, 3.10)

Income

  

 < £30,999

Reference

1.15 (1.06, 1.26)

 ≥ £30,999

1.06 (0.97, 1.16)

1.26 (1.15, 1.38)

Total physical activity MET-hours/week

  

 ≥ 60%

Reference

1.19 (1.08, 1.32)

 < 60%

1.20 (1.10, 1.31)

1.36 (1.25, 1.48)

Alcohol consumption

  

 Special occasions or never or moderate

Reference

1.17 (1.08, 1.25)

 Heavy

1.13 (1.05, 1.22)

1.33 (1.23, 1.44)

  1. *P for interaction < 0.01