Table 3 Comparison of AL score by selected characteristics between all cohort and breast cancer cases
From: Association between allostatic load and breast cancer risk: a cohort study
| Â | AL, mean, (SD) | Â | |
|---|---|---|---|
|  | All cohort (N = 181,455) | Case (N = 5,701) | P value |
Age at recruitment, median | Â | Â | Â |
 < 57 years old | 2.16 (1.70) | 2.20 (1.70) | 0.23 |
 ≥ 57 years old | 3.07 (1.67) | 3.19 (1.68) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Race | Â | Â | Â |
 White | 2.62 (1.73) | 2.77 (1.76) |  < 0.01 |
 Black | 2.87 (1.83) | 2.87 (1.75) | 0.96 |
 Asian | 3.05 (1.87) | 3.18 (1.71) | 0.46 |
 Mixed or others | 2.58 (1.73) | 2.56 (1.73) | 0.92 |
 P value | 0.06 |  < 0.01 |  |
Age at first live birth | Â | Â | Â |
 < 30 years old | 2.82 (1.74) | 2.94 (1.74) |  < 0.01 |
 ≥ 30 years old | 2.16 (1.64) | 2.39 (1.73) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Age at menarche | Â | Â | Â |
 < 10 years old | 2.82 (1.74) | 3.03 (1.85) | 0.02 |
 ≥ 10 years old | 2.16 (1.64) | 2.61 (1.73) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Ever taken oral contraceptive pill | Â | Â | Â |
 Yes | 2.55 (1.73) | 2.69 (1.74) |  < 0.01 |
 No | 2.97 (1.75) | 3.11 (1.78) | 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Ever used hormone-replacement therapy | Â | Â | Â |
 Yes | 2.97 (1.68) | 3.09 (1.66) |  < 0.01 |
 No | 2.43 (1.74) | 2.55 (1.79) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Had menopause | Â | Â | Â |
 Yes | 2.87 (1.68) | 3.02 (1.69) |  < 0.01 |
 No | 1.85 (1.61) | 1.83 (1.58) | 0.64 |
 P value |  < 0.01 |  < 0.01 |  |
Family history of breast cancer | Â | Â | Â |
 Yes | 2.72 (1.74) | 2.84 (1.74) |  < 0.01 |
 No | 2.50 (1.69) | 2.72 (1.76) | 0.01 |
 P value |  < 0.01 | 0.17 |  |
Education | Â | Â | Â |
 High school or less | 2.63 (1.73) | 2.78 (1.74) |  < 0.01 |
 College/professional | 2.32 (1.66) | 2.49 (1.73) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Employment | Â | Â | Â |
 Unemployment | 2.71 (1.85) | 2.91 (1.94) | 0.03 |
 Employment | 2.30 (1.68) | 2.43 (1.71) |  < 0.01 |
 Retired | 3.16 (1.66) | 3.25 (1.66) | 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Income | Â | Â | Â |
 < £30,999 | 2.93 (1.75) | 3.08 (1.77) |  < 0.01 |
 ≥ £30,999 | 2.21 (1.77) | 2.38 (1.67) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Cigarette smoking | Â | Â | Â |
 Never | 2.56 (1.73) | 2.71 (1.75) |  < 0.01 |
 Ever | 2.77 (1.74) | 2.91 (1.80) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Total physical activity MET-hours/week | Â | Â | Â |
 < 20% | 2.87 (1.81) | 2.93 (1.84) | 0.30 |
 20 ~ 40% | 2.58 (1.74) | 2.79 (1.74) |  < 0.01 |
 40 ~ 60% | 2.47 (1.69) | 2.56 (1.69) | 0.14 |
 60 ~ 80% | 2.41 (1.67) | 2.58 (1.67) |  < 0.01 |
 ≥ 80% | 2.44 (1.65) | 2.57 (1.71) | 0.04 |
 P value |  < 0.01 |  < 0.01 |  |
Alcohol consumption | Â | Â | Â |
 Special occasions or never | 3.06 (1.84) | 3.26 (1.88) |  < 0.01 |
 Moderate | 2.60 (1.74) | 2.73 (1.75) |  < 0.01 |
 Heavy | 2.38 (1.62) | 2.53 (1.64) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |
Sleep quality | Â | Â | Â |
 Never/rarely sleepless | 2.34 (1.71) | 2.45 (1.72) | 0.04 |
 Sometimes sleepless | 2.62 (1.72) | 2.78 (1.75) |  < 0.01 |
 Usually sleepless | 2.84 (1.76) | 2.95 (1.76) |  < 0.01 |
 P value |  < 0.01 |  < 0.01 |  |