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Table 2 Information of post-BCS patients’ characteristics

From: Molecular subtypes of breast cancer predicting clinical benefits of radiotherapy after breast-conserving surgery: a propensity-score-matched cohort study

Variables

Post-BCS patients after 1:1 PS match

p value

RT N = 6582 (%)

 

No RT N = 6582 (%)

Age group (years)

  

0.96

 20–46

1578 (23.97)

1594 (24.22)

 

 47–52

1490 (22.64)

1468 (22.30)

 

 53–60

1534 (23.31)

1542 (23.43)

 

  > 60

1980 (30.08)

1978 (30.05)

 

Subtype

  

0.74

 Luminal A

2646 (40.20)

2607 (39.61)

 

 Luminal B/HER2 -

373 (5.67)

396 (6.02)

 

 Luminal B/HER2+

667 (10.13)

705 (10.71)

 

 Basal-like

390 (5.93)

398 (6.05)

 

 HER2-enriched

382.00 (5.80)

394 (5.99)

 

 Unknown

2124 (32.27)

2082 (31.63)

 

RT dose (cGy)

  

 < 0.0001

 0

–

6582 (100)

 

 3000–5040

711 (10.80)

–

 

 5040–6040

4037 (61.33)

–

 

  > 6040

1834 (27.86)

–

 

C-stage

  

0.42

 0

423 (6.43)

445 (6.76)

 

 I

3231 (49.09)

3173 (48.21)

 

 II

2607 (39.61)

2627 (39.91)

 

 III

208 (3.61)

237 (3.60)

 

 IV

113 (1.72)

100 (1.52)

 

P-stage

  

0.21

 0

184 (2.80)

194 (2.95)

 

 I

3412 (51.84)

3307 (50.24)

 

 II

2300 (34.94)

2330 (35.40)

 

 III

310 (4.71)

364 (5.53)

 

 IV

108 (1.64)

102 (1.55)

 

 Unknown

268 (4.07)

285 (4.33)

 

Comorbidities

   

 COPD

263 (4.00)

292 (4.44)

0.20

 Hypertension

1565 (23.78)

1537 (23.35)

0.56

 Diabetes mellitus

667 (10.13)

710 (10.79)

0.22

 CKD

132 (2.01)

153 (2.32)

0.20

 Heart failure

40 (0.61)

46 (0.70)

0.51

 Liver disease

326 (4.95)

371 (5.64)

0.07

 Liver cirrhosis

24 (0.36)

23 (0.35)

0.88

Chemotherapy

3083 (46.84)

3101 (47.11)

0.75

Hormone therapy

5016 (76.21)

4959 (75.34)

0.24

Target therapy

345 (5.24)

400 (6.08)

0.03

Anti-cancer agents

   

 Doxorubicin

616 (9.36)

464 (7.05)

 < 0.0001

 Epirubicin

1797 (27.30)

1709 (25.96)

0.08

 Docetaxel

1297 (19.71)

1037 (15.76)

 < 0.001

 Paclitaxel

189 (2.87)

206 (3.13)

0.38

 Carboplatin

15 (0.23)

22 (0.33)

0.24

 Cyclophosphamide

2895 (43.98)

2827 (42.95)

0.23

 Fluorouracil

1795 (27.27)

1804 (27.41)

0.86

 Methotrexate

218 (3.31)

283 (4.30)

0.003

Family income (NTD per month)

  

0.95

  < 20,100

1636 (24.86)

1653 (25.11)

 

 20,101–22,800

1138 (17.29)

1148 (17.44)

 

 22,801–42000

2007 (30.49)

1978 (30.05)

 

  > 42,000

1801 (27.36)

1803 (27.39)

 

Urbanization level

  

0.70

 City

1817 (27.61)

1776 (26.98)

 

 Satellite cities

3462 (52.60)

3482 (52.90)

 

 Rural areas

1303 (19.80)

1324 (20.12)

 

Geographic region

  

0.06

 North

3016 (45.82)

3064 (46.55)

 

 Central

1637 (24.87)

1630 (24.76)

 

 South

1839 (27.94)

1764 (26.80)

 

 East

90 (1.37)

124 (1.88)

 
  1. PS propensity score, BCS breast-conserving surgery, RT radiotherapy, C-stage clinical stage, P-stage pathological stage, BCS breast-conserving surgery, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, NTD New Taiwan dollar, Insurance premium for National Health Insurance is according to family income