Fig. 1From: Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathwayManhattan plot of association results between chemotherapy and DNA methylation for 588,798 probes (125 breast cancer patients with pre- and post-chemotherapy paired samples), adjusted for the proportion of monocytes (limma design matrix ~ 0 + time + serial + monocytes). The term “time” refers to the specific time at which the sample was collected (i.e. pre- or post-chemotherapy). The term “serial” denotes the patient’s unique study ID. Using a Bonferroni threshold p-value < 8.49e-8, represented by a red line, a total of 1568 associations were found to be statistically significant (Additional file 3)Back to article page