Single-cell transcriptomics provide insight into metastasis-related subsets of breast cancer

Breast Cancer Research

Table 1 Sample, molecular characteristics, function, and reference of cell subpopulations

Cell subpopulations	Sample	Molecular characteristics	Function	References
ARTN + L1CAM + epi_tum1	Primary Cancer	ARTN, L1CAM	Promotes angiogenesis and metastasis	Shi et al
HMGA1-high Cancer Stem Cell	Axillary lymph	HMGA1	Promote lymph node metastasis	Nakayama et al
Early-disseminated Cancer Cell	Axillary lymph	COX6C, DHRS2	Metastasis of energy metabolism	Liu et al
CXCL14 + Cancer Cell	Lymph node	CXCL14, KAT6B	Evade immune surveillance during metastasis	Xu et al
Osteoclast-like giant Cell	Lymph node	MMP9, CST3, CD68	Promote the growth of metastatic cells	Xu et al
Lung L3 Cancer Stem Cell	Lung	ALDH1A1, ABCG2	Promote lung metastasis	Xu et al
TREM2 + Macrophage	Bone marrow	TREM2, CD68	Promote bone marrow metastasis	Molgora et al
Dormant Cancer Cell	Tissue	CFH, GAS6	Promotes bone/cerebrospinal fluid metastasis	Bidard et al

ISSN: 1465-542X