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Fig. 3 | Breast Cancer Research

Fig. 3

From: Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms

Fig. 3

Association of immunohistochemical (IHC) PD-L1 expression with PD-L1 (CD274) gene expression (mRNA) in the overall cohort. In AD the association of gene expression with SP142 PD-L1 staining in immune cells (ICs), 22C3 combined positive score (CPS) ≥ 1, 22C3 IC staining and 22C3 CPS ≥ 10, respectively, all at two-categorical IHC expressions. In E the association of gene expression with 22C3 CPS at three-categorical IHC expression. The mRNA expression of the SP142 IC and 22C3 CPS concordant and discordant cases in (F) and (G), with CPS threshold of 1 and 10, respectively

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