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Table 1 Clinicopathologic characteristics of the luminal-like MBC cohort.

From: Interplay between ESR1/PIK3CA codon variants, oncogenic pathway alterations and clinical phenotype in patients with metastatic breast cancer (MBC): comprehensive circulating tumor DNA (ctDNA) analysis

Characteristics

No

%

BC histological type

 NST

509

84.55

 Lobular

93

15.45

BC IHC characteristics

 ER + 

697

99.15

 PR + 

464

66.67

 HER2+

0

0

Metastatic involvement

 Bone

548

78.06

 Liver

290

41.31

 Lymph nodes

262

37.32

 Lung

221

31.48

 Soft tissue

125

17.81

 CNS

46

6.55

Previous treatments

 ET

452

74.10

 CT

257

42.13

 CDK4/6 inhibitors

322

52.79

 mTOR inhibitors

105

17.21

 PI3K inhibitors

38

6.23

 Immunotherapy

8

1.31

  1. NST (Non-Special Type), CNS (Central Nervous System), ET (Endocrine Therapy), CT (Chemotherapy)