Skip to main content
Fig. 7 | Breast Cancer Research

Fig. 7

From: The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling

Fig. 7

ZBC260 decreases the expression of STAT genes and proteins. (a–c) Effect of ZBC260 or vehicle treatment on multiple STAT gene expression in ALDH− and ALDH+ cell populations of SUM159 cells. Expression of genes was normalized to GAPDH (d–g) Western blot analysis of Stat proteins in ALDH− and ALDH+ cell populations of SUM159 cells treated with ZBC260. Protein expression was normalized to β-Actin. Data points are the mean ± SEM for individual experiments, n = 3 independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. The results presented are representative graphs of at least 3 biological replicates

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us