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Fig. 5 | Breast Cancer Research

Fig. 5

From: The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling

Fig. 5

ZBC260 modulates specific pathways in ALDH+ cells. a Venn diagram depicting the number of significantly modulated shared or unique pathways in SUM159 ALDH+ and ALDH− cells after ZBC260 treatment. b Pathways significantly regulated in ALDH+ and ALDH− populations cells after ZBC260 treatment. c Top 20 significantly downregulated genes identified in significantly modulated pathways in ALDH+ cells after ZBC260 treatment. FDR (P < 0.05) was considered significant. Statistics by Benjamini–Hochberg multiple comparisons test, n = 3 independent experiments

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Breast Cancer Research

ISSN: 1465-542X

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