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Table 4 Multivariable logistic regression for detected breast cancers and false positive recall

From: Impact of breast density on diagnostic accuracy in digital breast tomosynthesis versus digital mammography: results from a European screening trial

Characteristics

Cancer DBT

Cancer DM

FP DBT

FP DM

Adjusted OR (95% CI)

p Value

Adjusted OR (95% CI)

p Value

Adjusted OR (95% CI)

p Value

Adjusted OR (95% CI)

p Value

PD 1

1—Reference

 

1—Reference

 

1—Reference

 

1—Reference

 

PD 2

1.25 (0.68–2.27)

0.48

1.21 (0.62–2.39)

0.58

2.23 (1.43–3.48)

 < 0.001

2.06 (1.22–3.47)

0.007

PD 3

1.68 (0.95–2.98)

0.08

1.80 (0.96–3.39)

0.07

1.85 (1.85–4.39)

 < 0.001

2.39 (1.43–3.97)

0.001

PD 4

1.69 (0.94–3.05)

0.08

1.62 (0.83–3.15)

0.16

2.82 (1.83–4.35)

 < 0.001

2.84 (1.72–4.68)

 <0 .001

PD 5

2.56 (1.41–4.65)

0.002

1.69 (0.82–3.50)

0.16

3.67 (2.39–5.63)

 <0 .001

3.06 (1.85–5.05)

 < 0.001

Trend PD

1.24 (1.09–1.42)

0.001

1.15 (0.98–1.34)

0.08

1.27 (1.17–1.38)

 < 0.001

1.24 (1.13–1.37)

 < 0.001

Postmenopausal

3.04 (1.94–4.78)

 < 0.001

2.71 (1.60–4.56)

 < 0.001

0.63 (0.50–0.78)

 < 0.001

0.66 (0.50–0.86)

0.002

Previous Screening

0.81 (0.42–1.56)

0.52

1.34 (0.53–3.42)

.54

0.82 (0.62–1.09)

0.17

0.82 (0.58–1.16)

0.27

DA 1

1—Reference

 

1—Reference

 

1—Reference

 

1—Reference

 

DA 2

1.37 (0.74–2.54)

0.32

1.32 (0.69–2.50)

0.40

1.17 (0.78–1.74)

0.45

1.16 (0.73–1.83)

0.53

DA 3

1.47 (0.85–2.90)

0.15

1.24 (0.64–2.41)

0.53

1.50 (1.03–2.19)

0.03

1.28 (0.82–2.00)

0.28

DA 4

2.43 (1.36–4.35)

0.003

1.70 (0.89–3.23)

0.11

1.85 (1.29–2.66)

0.001

1.41 (0.91–2.18)

0.13

DA 5

2.60 (1.42–4.76)

0.002

1.54 (0.77–3.10)

0.22

2.25 (1.57–3.22)

 < 0.001

2.13 (1.40–3.23)

 < 0.001

Trend DA

1.28 (1.12–1.46)

 < 0.001

1.12 (0.96–1.30)

0.14

1.23 (1.14–1.33)

 < 0.001

1.20 (1.10–1.32)

 < 0.001

Postmenopausal

3.00 (1.93–4.67)

 < 0.001

2.67 (1.60–4.47)

 < 0.001

0.60 (0.48–0.75)

 < 0.001

0.63 (0.48–0.83)

0.001

Previous Screening

0.80 (0.42–1.55)

0.51

1.34 (0.52–3.41)

0.54

0.81 (0.61–1.08)

0.15

0.82 (0.58–1.16)

0.26

  1. DBT digital breast tomosynthesis; OR odds ratio; CI confidence interval; DM digital mammography; FP false positive; PD breast percent density; DA absolute dense area