Immune marker expressions | Â | PFS (%) | P value | OS (%) | P value |
---|---|---|---|---|---|
In tumor cells | |||||
PD-1 | Negative (N = 227) | 85.5 | – | 92.5 | – |
 | Positive (N = 0) | 0 |  | 0 |  |
PD-L1 | Negative (N = 181) | 83.4 | 0.081 | 91.7 | 0.348 |
 | Positive (N = 46) | 93.5 |  | 95.7 |  |
PD-L2 | Negative (N = 30) | 90.0 | 0.494 | 96.7 | 0.378 |
 | Positive (N = 197) | 84.8 |  | 91.9 |  |
IDO | Negative (N = 98) | 84.7 | 0.640 | 89.8 | 0.145 |
 | Positive (N = 129) | 86.0 |  | 94.6 |  |
TIM3 | Negative (N = 118) | 83.9 | 0.538 | 94.1 | 0.369 |
 | Positive (N = 109) | 87.2 |  | 90.8 |  |
OX40 | Negative (N = 145) | 89.7 | 0.025 | 94.5 | 0.181 |
 | Positive (N = 82) | 78.0 |  | 89.0 |  |
OX40L | Negative (N = 141) | 87.9 | 0.224 | 93.6 | 0.475 |
 | Positive (N = 86) | 81.4 |  | 90.7 |  |
B7-H2 | Negative (N = 34) | 97.1 | 0.054 | 94.1 | 0.782 |
 | Positive (N = 193) | 83.4 |  | 92.2 |  |
In immune cells | |||||
PD-1 | Negative (N = 101) | 80.2 | 0.040 | 90.1 | 0.208 |
 | Positive (N = 126) | 89.7 |  | 94.4 |  |
PD-L1 | Negative (N = 136) | 80.9 | 0.020 | 90.4 | 0.163 |
 | Positive (N = 91) | 92.3 |  | 95.6 |  |
PD-L2 | Negative (N = 119) | 81.5 | 0.086 | 90.8 | 0.296 |
 | Positive (N = 108) | 89.8 |  | 94.4 |  |
IDO | Negative (N = 73) | 84.9 | 0.823 | 93.2 | 0.882 |
 | Positive (N = 154) | 85.7 |  | 92.2 |  |
TIM3 | Negative (N = 123) | 82.1 | 0.100 | 90.2 | 0.149 |
 | Positive (N = 104) | 89.4 |  | 95.2 |  |
OX40 | Negative (N = 143) | 84.6 | 0.564 | 91.6 | 0.452 |
 | Positive (N = 84) | 86.9 |  | 94.0 |  |
OX40L | Negative (N = 124) | 80.6 | 0.020 | 90.3 | 0.157 |
 | Positive (N = 103) | 91.3 |  | 95.1 |  |
B7-H2 | Negative (N = 77) | 83.1 | 0.502 | 90.9 | 0.523 |
 | Positive (N = 150) | 86.7 |  | 93.3 |  |