Fig. 7
From: Human basal-like breast cancer is represented by one of the two mammary tumor subtypes in dogs
PGR is associated with gene silencing in canine tumors but not in human tumors. A Venn diagrams indicating the number of genes that are positively correlated with ESR1 and/or PGR in mRNA expression in each human or canine subtype specified. These genes were identified as those having correlation coefficient \(R>0.3\) and BH-adjusted \(p<0.05\) in both Pearson and Spearman correlation analyses. Also indicated are the top enriched functions of genes that are correlated with only ESR1 or PGR. B Venn diagrams for genes negatively correlated with ESR1 and/or PGR, identified with \(R<- 0.3\) and other cutoffs and presented as described in A