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Fig. 6 | Breast Cancer Research

Fig. 6

From: Human basal-like breast cancer is represented by one of the two mammary tumor subtypes in dogs

Fig. 6

PGR correlates with several T cell exhaustion signature genes in mRNA expression in ER−PR+ cBLMTs. A Dot plots of log2(TPM) values of IFNG and 8 canonical T cell exhaustion marker genes in each cBLMT subgroup and cNBLMT. P-values are from Wilcoxon tests. **: p < 0.01; ***: p < 0.001; ****: p < 0.0001. B–D Pearson (top) and Spearman (bottom) correlation analysis between PGR B, ESR1 C, or PRLR D and PDCD1, HAVCR2, CTLA4, or TIGIT in mRNA expression in each subgroup and subtype shown. Only significant Pearson and/or Spearman correlations have p-values indicated

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