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Fig. 5 | Breast Cancer Research

Fig. 5

From: Single-cell RNA reveals a tumorigenic microenvironment in the interface zone of human breast tumors

Fig. 5

Endothelial cell clusters. a tSNE plots of 1258 endothelial cells, color by relevant clusters (top) or sample type (bottom). b Color coding for expressions (gray to blue) of marker genes of lymphatic and vascular endothelial cells. ECs, endothelial cells. c Differences in the score of pathway activity of each cell by GSVA, between endothelial cells isolated from tumor or interface zone. d Violin plots displaying expressions of the selected genes in endothelial cells from tumor, interface and normal zones. e Differences in pathway activity of each cell scored by GSVA between zone-specific vascular endothelial cells (clusters 2, 4, 6 and 8). f Heatmap of single-cell regulon scores inferred by SCENIC. Number in brackets is the number of the target genes. g, genes

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