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Fig. 1 | Breast Cancer Research

Fig. 1

From: Single-cell RNA reveals a tumorigenic microenvironment in the interface zone of human breast tumors

Fig. 1

Overview of the 88,548 single cells from breast tissues of breast cancer patients. a Design and workflow of this study. b tSNE plots of the 88,548 cells profiled (top to bottom): the annotated cell type, different patients of origin (patient 1, patient 2 and patient 3), different sample types of origin (normal, interface or tumor zone samples) and the number of transcripts. K, Thousand. c Density dot plot showing the correlation of genes in bulk sequencing and single-cell sequencing. d Subclusters of stem cells, macrophages, T cells, B cells, endothelial cells, fibroblasts and epithelial cells (left to right): tSNE plots of marker genes for cell types, the fraction of cells deriving from each of 3 patients, the fraction of cells deriving from the normal, interface and tumor zone samples and the number of cells in each subcluster

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