Fig. 1From: SCR-6852, an oral and highly brain-penetrating estrogen receptor degrader (SERD), effectively shrinks tumors both in intracranial and subcutaneous ER + breast cancer modelsDocking diagram of SCR6139, SCR6515, and ERα-LBD complex. a SCR6139 and SCR6515 were docked to ERα-LBD complex (PDB: 6ZOQ; the crystal ligand in 6ZOQ (carmine), SCR6139 (blue), SCR6515 (green). b Schematic diagram of two-dimensional interaction for SCR6139Back to article page