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Fig. 1 | Breast Cancer Research

Fig. 1

From: Enhancement of PD-L1-attenuated CAR-T cell function through breast cancer-associated fibroblasts-derived IL-6 signaling via STAT3/AKT pathways

Fig. 1

Characterization of primary culture fibroblasts. Immunofluorescence using antibodies directed to specific markers for epithelial cells (panCK, red fluorescence), fibroblast intermediate filament (VIM, red fluorescence), myofibroblasts (ASMA, red fluorescence), fibroblast-associated protein (FAP, green fluorescence), and chemotactic receptor (CD10, green fluorescence; GPR77, red fluorescence) of different primary culture fibroblasts and normal fibroblasts (HDF and BNF). The nuclei were counterstained with Hoechst. All images were captured at 200 × magnification, scale bars = 50 μm. NFs, normal fibroblasts; HDF, human dermal fibroblast; BNF, breast normal fibroblast; CAFs, cancer-associated fibroblasts; panCK, pan-cytokeratin; VIM, vimentin; ASMA, alpha-smooth muscle actin; FAP, fibroblast activation protein; CD10, a cluster of differentiation 10; GPR77, G protein-coupled receptor 77

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Breast Cancer Research

ISSN: 1465-542X

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