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Table 2 The association between pCR and IHC molecular subtype as well as image molecular subtypes was quantified with odds ratio

From: Noninvasive imaging signatures of HER2 and HR using ADC in invasive breast cancer: repeatability, reproducibility, and association with pathological complete response to neoadjuvant chemotherapy

 

Discovery

Validation

Image signature

IHC

Image signature

IHC

OR

P value

OR

P value

OR

P value

OR

P value

HER2 + versus HER2-

2.65

0.025

3.83

0.003

4.73

0.006

4.13

0.018

HR +  versus HR-

0.29

0.005

0.38

0.024

0.29

0.021

0.32

0.038

HER2-HR +  versus non-HER2-HR + 

0.15

0.002

0.25

0.002

0.12

0.001

0.23

0.011

HER2-HR- versus non-HER2-HR-

1.26

0.663

1.19

0.828

1.42

0.572

1.28

0.787

HER2 + HR +  versus non-HER2 + HR + 

0.98

1.000

1.64

0.425

2.04

0.236

1.49

0.526

HER2 + HR- versus non-HER2 + HR-

3.66

0.007

11.29

0.001

8.65

0.009

28.33

0.002

  1. The significant P value was bold
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Breast Cancer Research

ISSN: 1465-542X

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