Fig. 6
From: Transcriptionally regulated miR-26a-5p may act as BRCAness in Triple-Negative Breast Cancer
In vivo effect of miRNA-26a-5p on the Cisplatin sensitivity. A, B The indicated cells were implanted orthotopically into the second mammary fat pad (i.m.f.p.) of female BALB/C nude mice. The volumes of subcutaneous tumors in the indicated groups (n = 3) were recorded. C RTV was introduced to illustrate Cisplatin effect on Cisplatin sensitivity in vivo. D, E T/C% was introduced to evaluate drug efficacy in vivo. F–H Representative images of IHC staining and the relative scores (n = 12) of the indicated markers in subcutaneous tumors of mice. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 versus control. N.S not significant