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Fig. 4 | Breast Cancer Research

Fig. 4

From: Long noncoding RNA PVT1 promotes breast cancer proliferation and metastasis by binding miR-128-3p and UPF1

Fig. 4

miR-128-3p was a target of PVT1 in BC cells. A The predicted interaction between PVT1 and miR-128-3p and the mutated miRNA binding site. B The expression levels of miR-128-3p in BC cell lines and the breast epithelial cell line HBL-100. C The plasma levels of miR-128-3p in 70 healthy controls, 70 fibroma patients, and 80 BC patients. D Luciferase reporter assays in 293 T cells. E The expression levels of miR-128-3p in Hs578t and MCF-7 cells with PVT1 knockdown. F The expression levels of miR-128-3p of tumor tissues from nude mice treated with si-NC and si-PVT1. Results were presented as the mean ± SD. **p < 0.01, ***P < 0.001

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