Predicted 25(OH)D (quartiles) | Breast cancer cases | Person-years | Age + period IRR | 95 % CI | MV IRRa | 95 % CI | P trend |
---|---|---|---|---|---|---|---|
All cases | |||||||
4 (highest) | 338 | 183,614 | 1.00 | Ref | 1.00 | Ref | 0.015 |
3 | 351 | 183,625 | 1.02 | 0.88, 1.19 | 1.08 | 0.93, 1.26 | |
2 | 365 | 183,603 | 1.02 | 0.88, 1.18 | 1.12 | 0.95, 1.31 | |
1 (lowest) | 400 | 183,568 | 1.06 | 0.92, 1.23 | 1.23 | 1.04, 1.46 | |
ER- cases | |||||||
4 (highest) | 109 | 183,326 | 1.00 | Ref | 1.00 | Ref | 0.42 |
3 | 100 | 183,346 | 0.90 | 0.68, 1.18 | 0.94 | 0.71, 1.25 | |
2 | 109 | 183,336 | 0.93 | 0.71, 1.21 | 1.02 | 0.77, 1.36 | |
1 (lowest) | 115 | 183,324 | 0.94 | 0.72, 1.22 | 1.12 | 0.82, 1.52 | |
ER+ cases | |||||||
4 (highest) | 182 | 183,430 | 1.00 | Ref | 1.00 | Ref | 0.035 |
3 | 192 | 183,446 | 1.05 | 0.86, 1.29 | 1.12 | 0.91, 1.38 | |
2 | 215 | 183,403 | 1.13 | 0.93, 1.38 | 1.25 | 1.01, 1.55 | |
1 (lowest) | 213 | 183,415 | 1.08 | 0.88, 1.32 | 1.26 | 1.00, 1.58 |