Skip to main content

Table 1 Correlation of paired expression levels in five genes reported in breast cancer (complete list of 18 genes in Additional file 2: Table S2) and nine genes identified by Jeselsohn

From: Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas

 

STUDY I

STUDY II

STUDY I vs. STUDY II

 

Gene symbol

R

p value

Geometric mean of B/A

95 % CI

R

p value

Geometric mean of S/D

95 % CI

Z value

p value (2 tail)

 

BAG1

0.713

0.0001

0.971

0.946-0.996

0.734

<0.0001

1.043

0.984-1.106

-0.17

0.865

MKi67

0.354

0.0978

1.009

0.962-1.058

0.522

<0.0001

0.977

0.930-1.027

-0.8

0.4237

MAPT

0.847

<0.0001

0.806

0.692-0.938

0.811

<0.0001

1.108

0.965-1.273

0.44

0.6599

PGR

0.522

0.0106

1.093

0.946-1.263

0.824

<0.0001

0.978

0.894-1.070

-2.25

0.0244

SNAI2

0.430

0.0408

0.897

0.790-1.018

0.481

0.0002

0.940

0.838-1.054

-0.25

0.8026

Genes that significantly changed in Jeselsohn et al. (2013) [6]

(a) immune related

IGFBP2

0.583

0.0035

1.051

0.862-1.282

0.784

<0.0001

1.136

1.031-1.251

-1.48

0.1389

IL6

0.712

0.0001

1.108

1.003-1.223

0.194

0.1525

1.167

1.079-1.262

2.65

0.008

CD68

0.412

0.0509

1.065

0.889-1.272

0.464

0.0003

1.099

0.985-1.226

-0.25

0.8026

CD14

0.553

0.0062

1.047

0.905-1.211

0.355

0.0074

1.017

0.901-1.148

0.96

0.3371

CD52

0.755

<0.0001

1.085

0.923-1.276

0.436

0.0008

1.038

0.876-1.230

1.97

0.0488

CD44

0.458

0.0278

0.927

0.788-1.091

0.816

<0.0001

0.952

0.890-1.019

-2.48

0.0131

PPARG

0.315

0.1438

0.806

0.608-1.068

0.343

0.0096

0.993

0.870-1.132

-0.12

0.9045

ADM

0.476

0.0217

0.931

0.720-1.204

0.544

<0.0001

1.122

0.964-1.306

-0.35

0.7263

VEGFA

0.653

0.0007

1.043

0.967-1.124

0.647

<0.0001

0.991

0.930-1.055

0.04

0.9681

(b) non-immune related

CENPF

0.781

<0.0001

1.039

0.913-1.183

0.729

<0.0001

1.062

0.959-1.176

0.46

0.6455

MYC

0.509

0.0132

1.076

0.897-1.292

0.65

<0.0001

1.439

1.241-1.668

-0.82

0.4122

CCNB1

0.413

0.0501

0.976

0.883-1.078

0.469

0.0003

1.010

0.919-1.107

-0.27

0.7872

MAP1LC3B

0.598

0.0026

0.957

0.882-1.038

0.809

<0.0001

0.971

0.933-1.010

-1.65

0.099

SNAI1

ND

ND

ND

ND

ND

ND

ND

ND

ND

ND

  1. ND non-detected