Figure 4

Kaplan-Meier curves based on the C1Q-HLA score. A score was calculated as the mean value of the C1Q signature minus the mean value of the HLA signature for each of 504 tumors with survival data from The Cancer Genome Atlas database. (A) All breast cancers were grouped in three quantiles of the C1Q-HLA score, and Kaplan-Meier curves were generated. Basal-like (B) and luminal B (C) breast cancers were grouped on the basis of the C1Q-HLA score above or below the median. Cox indicates the hazard ratio (HR) and P values obtained when the C1Q-HLA score was used as a continuous variable together with lymph node status in a multivariate Cox proportional hazard model.