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Figure 2 | Breast Cancer Research

Figure 2

From: Imaging in situ breast carcinoma (with or without an invasive component) with technetium-99m pentavalent dimercaptosuccinic acid and technetium-99m 2-methoxy isobutyl isonitrile scintimammography

Figure 2

A 5-cm infiltrating ductal carcinoma, grade 2, with 9-cm, comedo-type, ductal carcinoma in situ of the right breast (patient 4). (a) Mammography, medio-lateral projection. Nodule with spiky margins (transparent arrow), close to the chest wall in the upper breast hemisphere. (b) Scintimammography, right lateral projection: 99mTc-Sestamibi (99mTc-MIBI) at 5 min and 60 min (upper row, i-ii); 99mTc-(V)DMSA at 10 min and 60 min (bottom row, iii-iv). Spindle-shaped focal accumulation (arrowhead) in the area corresponding to the radiological abnormality. The 60-min 99mTc-(V)DMSA image additionally reveals an extensive area of diffuse heterogeneous patchy tracer uptake (arrow) extending below and anterior to the margins of the focal accumulation. Lymph node involvement in the axilla is visible (curved arrow).

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