Table 4 Multivariate Cox regression models for disease-free survival and overall survival in patients with invasive ductal carcinoma and patients with invasive lobular carcinoma
From: Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome
| Â | DFS | OS | ||
|---|---|---|---|---|
Parameter | RR (95% CI) | P | RR (95% CI) | P |
Nodes | Â | Â | Â | Â |
   0 | 1 | <0.0001 | 1 | <0.0001 |
   1–3 | 1.8 (1.6–1.9) |  | 1.4 (1.3–1.5) |  |
   >3 | 3.4 (3.1–3.6) |  | 2.4 (2.2–2.5) |  |
Tumor size (cm) | Â | Â | Â | Â |
   ≤2 | 1 | <0.0001 | 1 | <0.0001 |
   2–5 | 1.5 (1.4–1.6) |  | 1.4 (1.3–1.5) |  |
   >5 | 1.9 (1.7–2.1) |  | 2.0 (1.8–2.1) |  |
Age (years) | Â | Â | Â | Â |
   ≤50 | 1 | 0.0005 | 1 | <0.0001 |
   >50 | 1.1 (1.0–1.2) |  | 1.9 (1.7–2.0) |  |
S-phase | Â | Â | Â | Â |
   Low | 1 | <0.0001 | 1 | <0.0001 |
   Intermediate | 1.4 (1.3–1.5) |  | 1.3 (1.2–1.3) |  |
   High | 1.5 (1.4–1.7) |  | 1.4 (1.3–1.5) |  |
PgR | Â | Â | Â | Â |
   Positive | 1 | <0.0001 | 1 | 0.0014 |
   Negative | 1.3 (1.2–1.4) |  | 1.3 (1.2–1.4) |  |
ER | Â | Â | Â | Â |
   Positive | 1 | 0.0017 | 1 | 0.048 |
   Negative | 1.1 (1.0–1.2) |  | 1.1 (1.0–1.2) |  |