Figure 2From: Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancersScoring by genomic scars of homologous recombination deficiency and drug response. Eight examples of various forms of structural copy number aberrations and rearrangements are given, whereby each box, lettered A to F, represents a genomic segment of approximately 3 Mbp in length. Below the chromosomes, the three genomic scars - homologous recombination defect (HRD), telomeric allelic imbalance score (NtAi), and large-scale transition (LST) - are listed along with the respective integer count for the scar (0 = not seen, 1 = detected once). LOH, loss of heterozygosity.Back to article page