Figure 1From: Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening studyMRE11, RAD50, and nibrin key functional domains. The protein domain diagrams are updated from Williams et al. [4] and include information from the InterPro protein sequence analysis and classification database, the Uniprot Protein Knowledgebase, and the NCBI Conserved Domains Database [47–50] plus structural studies of the MRN proteins [51–63].Back to article page