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Figure 2 | Breast Cancer Research

Figure 2

From: Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy

Figure 2

Association of the BRCA-likeCGHstatus with overall survival after HD-CTC and conventional chemotherapy. Kaplan-Meier survival curves for OS were generated separately for all HER2-negative breast cancer patients with BRCA-likeCGH(A) and with non-BRCA-likeCGH(B) tumors; for the subgroup of TNBC patients with BRCA-likeCGH(C) and with non-BRCA-likeCGH(D) tumors; and for the subgroup of hormone receptor-positive, HER2-negative breast cancer patients with BRCA-likeCGH(E) and with non-BRCA-likeCGH tumors (F); who had been randomly assigned between HD-PB chemotherapy and conventional chemotherapy. FE90C, 5-fluorouracil, epirubicin, cyclophosphamide; HD-CTC, high-dose cyclophosphamide-thiotepa-carboplatin; HD-PB, high-dose platinum-based; HR-pos, hormone receptor-positive; OS, overall survival; TNBC, triple-negative breast cancer.

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