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Table 1 Characteristics of participating breast cancer patients with ER+/HER2− tumors a

From: Clinical validation of the EndoPredict test in node-positive, chemotherapy-treated ER+/HER2− breast cancer patients: results from the GEICAM 9906 trial

Characteristics

Patients, n(%)

Measurement results

Patients, n(%)

Age, yr

 

ER (Allred score b )

 

  <50

250 (45%)

0

53 (9.6%)

  ≥50

305 (55%)

3

5 (0.9%)

Menopausal status

 

4

14 (2.5%)

  Premenopausal

300 (54%)

5

28 (5.1%)

  Postmenopausal

255 (46%)

6

66 (11.9%)

Nodal status

 

7

130 (23.4%)

  N1

357 (64%)

8

256 (46.1%)

  N2

151 (27%)

Unknown

3 (0.5%)

  N3

47 (9%)

PR (Allred score b )

 

T stage

 

0

104 (18.7%)

  1

252 (45%)

3

10 (1.8%)

  2

276 (50%)

4

14 (2.5%)

  3

27 (5%)

5

42 (7.6%)

Grade

 

6

48 (8.7%)

  1

91 (16%)

7

65 (11.7%)

  2

260 (47%)

8

268 (48.3%)

  3

157 (28%)

Unknown

4 (0.7%)

  Unknown

47 (9%)

Ki67 (%)

Median (min-max) = 5 (0 to 80)

Treatment arm

 

Low (<14%)

400 (72.1%)

  FEC

280 (50.5)

High (14%)

134 (24.1%)

  FEC-P

275 (49.5)

Unknown

21 (3.8%)

  1. aER: Estrogen receptor; FEC: Fluorouracil, epirubicin and cyclophosphamide; FEC-P: Fluorouracil, epirubicin and cyclophosphamide followed by weekly paclitaxel; HER2: Human epidermal growth factor receptor 2; PR: Progesterone receptor. bAllred et al. [18]. Patient data were drawn from the GEICAM 9906 trial (n = 555).