Table 1 BRCA1 Deficient-Like ( BD-L ) distribution in a breast cancer cell line panel

Cell line	ER	PR	HER2	BRCA1	*BD-L*metagene value
HCC1143	-	-	-	NA	207.2555
MDAMB415	+	-	-	wt/-	208.6937
HCC1937	-	-	-	m/-	226.181
BT20	-	-	-	wt/-	227.6686
MDAMB468	-	-	-	wt/-	260.2652
BT474	+	+	+	wt/-	261.2111
HCC1428	+	+	-	NA	265.375
MDAMB134VI	+	-	-	wt/wt	267.9736
SKBR3	-	-	+	wt/-	277.6819
MCF10A	-	-	-	NA	285.3522
HCC1954	-	-	+	NA	300.0448
HCC1500	-	-	-	NA	300.3202

Breast cancer cell lines selected for pharmacological inhibition evaluation. BD-L metagene values for the cell lines, as calculated from the Neve et al. [21] data set, are listed by increasing value. Estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) protein expression status are indicated. If known, the BRCA1 mutational status is noted (NA: not available).

ISSN: 1465-542X