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Table 3 Targeted qPCR analysis of mammary glands after 3, 4, or 10 weeks on HFD versus LFD

From: Pubertal high fat diet: effects on mammary cancer development

Inflammation PCR array

Fold change HFD versus LFD

Symbol

Description

3 wks MG

4 wks MG

10 wks MG

Ccl24

Chemokine (C-C motif) ligand 24

2.7

-

-

Ccl3

Chemokine (C-C motif) ligand 3

2.3

-

-

Il4

Interleukin 4

2.2

-

-

Il5ra

Interleukin 5 receptor, alpha

3.0

-

-

RANKL

Receptor activator of nuclear factor kappa-B ligand

-

17

-

Ccl1

Chemokine (C-C motif) ligand 1

-

-

4.5

Ccl17

Chemokine (C-C motif) ligand 17

-

-

3.2

Ccl19

Chemokine (C-C motif) ligand 19

-

-

7.5

Ccl20

Chemokine (C-C motif) ligand 20

-

-

5.2

Ccl22

Chemokine (C-C motif) ligand 22

-

-

7.6

Il1b

Interleukin 1 beta

-

-

2.1

Il2rb

Interleukin 2 receptor, beta chain

-

-

2.7

Cxcr2

Chemokine (C-X-C motif) receptor 2

-

-

4.3

Lta

Lymphotoxin A

-

-

3.2

Xcr1

Chemokine (C motif) receptor 1

-

-

2.5

  1. N = 3 high fat diet (HFD) mice, n = 3 low fat diet (LFD) mice; n = 3 mice with early developing tumors while on HFD (HFD-E), n = 3 LFD mice with tumors. P ≤0.05 for all genes listed.