ER H-scorea | Number of women | Number of deaths | Adjusted HR (95% CI) | |
---|---|---|---|---|
Model 1b | Model 2c | |||
Overall | Â | Â | Â | Â |
<1 (ER-negative) | 506 | 157 | Referent | Referent |
1 to 50 | 173 | 34 | 0.70 (0.48 to 1.03) | 0.81 (0.54 to 1.21) |
51 to 100 | 173 | 31 | 0.58 (0.39 to 0.87) | 0.68 (0.45 to 1.03) |
101 to 150 | 226 | 33 | 0.45 (0.31 to 0.67) | 0.53 (0.35 to 0.81) |
151 to 225 | 126 | 17 | 0.39 (0.23 to 0.65) | 0.48 (0.28 to 0.84) |
Trend |  |  | Ptrend <0.0001 | Ptrend = 0.0004 |
Trend in women with ER-positive tumors only |  |  | Ptrend = 0.008 | Ptrend = 0.02 |
Per 20 unit increase | Â | Â | 0.90 (0.86 to 0.94) | 0.92 (0.88 to 0.97) |
Per 20 unit increase in women with ER-positive tumors only | Â | Â | 0.90 (0.83 to 0.98) | 0.90 (0.84 to 0.99) |
White women | Â | Â | Â | Â |
<1 (ER-negative) | 251 | 69 | Referent | Referent |
1 to 50 | 107 | 22 | 0.66 (0.39 to 1.11) | 0.85 (0.48 to 1.52) |
51 to 100 | 104 | 17 | 0.46 (0.26 to 0.82) | 0.59 (0.32 to 1.09) |
101 to 150 | 141 | 18 | 0.34 (0.19 to 0.58) | 0.45 (0.24 to 0.83) |
151 to 225 | 78 | 5 | 0.20 (0.08 to 0.52) | 0.29 (0.11 to 0.76) |
Trend |  |  | Ptrend <0.0001 | Ptrend = 0.0006 |
Trend in women with ER-positive tumors only |  |  | Ptrend = 0.008 | Ptrend = 0.01 |
Per 20 unit increase | Â | Â | 0.69 (0.59 to 0.79) | 0.75 (0.64 to 0.88) |
Per 20 unit increase in women with ER-positive tumors only | Â | Â | 0.66 (0.49 to 0.90) | 0.68 (0.50 to 0.92) |
Black women | Â | Â | Â | Â |
<1 (ER-negative) | 255 | 88 | Referent | Referent |
1 to 50 | 66 | 12 | 0.51 (0.27 to 0.94) | 0.56 (0.30 to 1.06) |
51 to 100 | 69 | 14 | 0.66 (0.36 to 1.19) | 0.72 (0.39 to 1.35) |
101 to 150 | 85 | 15 | 0.55 (0.31 to 0.99) | 0.61 (0.33 to 1.11) |
151 to 225 | 48 | 12 | 0.54 (0.28 to 1.05) | 0.64 (0.32 to 1.28) |
Trend |  |  | Ptrend = 0.008 | Ptrend = 0.07 |
Trend in women with ER-positive tumors only |  |  | Ptrend = 0.41 | Ptrend = 0.59 |
Per 20 unit increase | Â | Â | 0.93 (0.88 to 0.98) | 0.95 (0.89 to 1.01) |
Per 20 unit increase in women with ER-positive tumors only | Â | Â | 0.96 (0.85 to 1.09) | 0.97 (0.86 to 1.10) |
Homogeneity between white women and black women | Â | Â | Â | |
Trend |  |  | Phomogeneity = 0.10 | Phomogeneity = 0.09 |
Trend in women with ER-positive tumors only |  |  | Phomogeneity = 0.05 | Phomogeneity = 0.02 |
Per 20 unit increase |  |  | Phomogeneity = 0.08 | Phomogeneity = 0.08 |
Per 20 unit increase in women with ER-positive tumors only |  |  | Phomogeneity = 0.05 | Phomogeneity = 0.02 |