Serum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohort

Table 3 Twenty-one differentially expressed microRNAs with a P value of not more than 0

Expression	microRNA	Pvalue^a	Percentage change	Previous reports in breast cancer tumor or cell lines
Overexpression	miR-1255a	0.00	10	No data
	miR-671-3p	0.01	7	No data
	miR-1827	0.01	14	No data
	miR-222	0.02	17	Overexpression [40, 58, 59]
	miR-744	0.02	10	No data
	miR-4306	0.03	8	No data
	miR-151-3p	0.03	15	Overexpression [60]
	miR-130b	0.03	14	Overexpression [61]
	miR-363	0.03	11	No data
	miR-149^a	0.03	12	No data
	miR-652	0.03	15	No data
	miR-320d	0.04	14	No data
	miR-18a	0.04	19	Overexpression [62–64]
	miR-181a	0.05	15	Overexpression [38, 65]
	miR-3136	0.05	4	No data
	miR-629	0.05	7	Overexpression [61]
Underexpression	miR-548d-5p	0.01	−4	No data
	miR-760	0.02	−9	No data
	miR-1234	0.03	−9	No data
	miR-18b^a	0.04	−5	Underexpression [63]
	miR-605	0.05	−7	No data

^aConditional logistic regression was used to test for differential gene expression in 414 microRNAs (miRNAs) expressed above background.

ISSN: 1465-542X