Table 1 Patient and tumor characteristics
Characteristics | Molecular apocrine No. patients (%) | Basal-like No. patients (%) |
|---|---|---|
All patients | 58 | 13 |
Age at diagnosis (range) | 54 y.o. (32 to 86) | 43 y.o. (27 to 63) |
Menopausal status - premenopausal - postmenopausal | 26 (45) 32 (55) | 10 (77) 3 (23) |
Clinical tumor size -T0-T1 -T2-T3-T4 | 11 (19) 47 (81) | 0 (0) 13 (100) |
Histology - Invasive ductal with Paget disease with apocrine differentiation with squamous metaplastic areas | 58 (100) 4 (7) 4 (7) 1 (2) | 13 (100) 1 (8) |
In situ component | 44 (76) | 3 (23) |
Pathological nodal involvment -N0 -N1, N2, N3 no axillary dissection | 22 (38) 33 (57) 3 (5) | 11 (85) 2 (15) |
Grading SBR -G2 -G3 | 15 (26) 43 (74) | 1 (8) 12 (92) |
Lymphovascular invasion | 28 (48) | 1 (8) |
Treatments: Surgery - lumpectomy - mastectomy - no Chemotherapy (CT) - neoadjuvant CT - adjuvant CT - neoadjuvant and adjuvant CT - no Radiotherapy Trastuzumab | 18 (31) 39 (67) 1 (2) 9 (15) 34 (59) 8 (14) 7 (12) 41 (71) 16 (28) | 0 (0) 13 (100) 0 (0) 0 (0) 1 (8) 12 (92) 0 (0) 10 (77) 0 (0) |