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Figure 4 | Breast Cancer Research

Figure 4

From: HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

Figure 4

Subpopulation treatment effect pattern plot (STEPP) analysis using the classical parameters human epidermal growth factor receptor 2 (HER2) silver in situ hybridization (SISH) copy number and hormone receptor immunohistochemistry. Shown are analysis for all tumors (A), hormone receptor-positive tumors (B) and hormone receptor negative tumors (C). In contrast to the data shown ins the classical parameters were not linked to pCR rate. pCR, pathological complete response; IHC, immunohistochemistry; HR, hormone receptor.

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