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Table 1 QSOX1 mRNA expression in relation to the usual prognostic factors in 217 breast IDC

From: High expression of QSOX1 reduces tumorogenesis, and is associated with a better outcome for breast cancer patients

Characteristics

 

n

%

median

P-value

Menopausal status

Pre

71

32.7

2.56

 
 

Post

146

67.3

3.31

0.003

Tumor size (mm)

<20

90

41.5

3.08

 
 

≥20

120

55.3

2.62

0.229

 

ND

7

3.2

3.38

 

Lymph node status

pN0

101

46.5

3.18

 
 

pN+

116

53.5

2.64

0.444

SBR Grade

I

30

13.8

4.25

 
 

II

115

53.0

3.14

 
 

III

58

26.7

1.74

<0.001

 

ND

14

6.5

2.42

 

ER status

Positive

179

82.5

3.17

 
 

Negative

38

17.5

1.51

<0.001

PgR status

Positive

169

77.9

3.17

 
 

Negative

48

22.1

1.97

<0.001

PAI-1 status*

Low

153

70.5

3.18

 
 

High

44

20.3

1.46

<0.001

 

ND

20

9.2

2.77

 
  1. P-values correspond to Mann-Whitney test or Kruskall Wallis test. ER, estrogen receptor; ND, Not Determined; PgR, Progesteron receptor; SBR, Scarff Bloom Richardson. *Low: ≤75% quartile; High: >75% quartile.