From: Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance
Variable | Marker | Â | Â | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  | CD44+CD24-/low | CD44-CD24+ | CD44+CD24+ | ALDH1A1 | Stromal ALDH1A1 | ALDH1A3 | Stromal ALDH1A3 | ITGA6 | Score | Total CSCs |
Allred score | 0 | 1, 808 (44) | 814 (20) | 1, 994 (48) | 2, 452 (59) | 1, 112 (27) | 1, 763 (43) | 2, 245 (54) | 2, 004 (49) | 0 | 1, 147 (28) |
 | 2 | 27 (1) | 18 (< 1) | 34 (1) | 169 (4) | 303 (7) | 43 (1) | 12 (< 1) | 20 (< 1) | 1 | 401 (10) |
 | 3 | 96 (2) | 241 (6) | 74 (2) | 95 (2) | 485 (12) | 183 (4) | 86 (2) | 106 (3) | 2 | 75 (2) |
 | 4 | 103 (3) | 318 (8) | 174 (4) | 69 (2) | 442 (11) | 162 (4) | 102 (2) | 77 (2) | 3 | 18 (< 1) |
 | 5 | 136 (3) | 310 (8) | 112 (3) | 40 (1) | 230 (6) | 120 (3) | 73 (2) | 50 (1) | 4 | 5 (< 1) |
 | 6 | 103 (3) | 358 (9) | 52 (1) | 27 (1) | 156 (4) | 194 (5) | 64 (2) | 39 (1) | Missing | 2, 479 (60) |
 | 7 | 104 (3) | 375 (9) | 74 (2) | 20 (< 1) | 130 (3) | 119 (3) | 27 (1) | 49 (1) |  |  |
 | 8 | 160 (4) | 103 (3) | 23 (1) | 18 (< 1) | 32 (1) | 27 (1) | 2 (< 1) | 44 (1) |  |  |
 | Missing | 1, 588 (39) | 1, 588 (39) | 1, 588 (39) | 1, 235 (30) | 1, 235 (30) | 1, 514 (37) | 1, 514 (37) | 1, 736 (42) |  |  |
Cut-off | Â | > 4 | > 3 | > 2 | > 4 | > 2 | > 6 | > 3 | > 4 | Â | NA |
Status* | Negative | 2, 034 (80) | 1, 073 (42) | 2, 028 (80) | 2, 785 (96) | 1, 415 (49) | 2, 465 (94) | 2, 343 (90) | 2, 207 (92) | Â | Â |
 | Positive | 503 (20) | 1, 464 (58) | 509 (20) | 105 (4) | 1, 475 (51) | 146 (6) | 268 (10) | 182 (8) |  |  |