Figure 4From: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAILc-FLIP L but not c-FLIP S knockdown sensitises breast cancer stem cells to TRAIL. BT474 and MDA-MB-231 cells were transfected with siRNA sequences targeted specifically to the short or long c-FLIP isoforms (FLIPi) or control siRNA (SCi). Cells were then plated in mammosphere culture and treated with 20 ng/ml TRAIL.Back to article page