Figure 3From: Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) miceAnalysis of the HER2-specific antibody response in sera of MMTV.f.huHER2(Fo5) transgenic mice. Mice were immunized with PBS (n = 4) (A) or anti-Id scFv69 (n = 5) (B). HER2-specific antibody level was measured in sera collected before the first immunization (pre-immune sera) and at the time of the maximum response during the study (Day 42) (immune sera). Each dot represents an immunized mouse.Back to article page