From: The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis
Stage | Increased risk (tumor subtype)* | Clinical characteristics |
---|---|---|
Pregnancy | ER- | High stage diagnosis |
 |  | High grade |
 |  | Often metastatic |
Postmenopause | ER+ | Lower grade at diagnosis |
 |  | Respond to anti-hormone therapies |
Postmenopause | ER- | High stage diagnosis |
with obesity | Â | Poor patient survival rate |