Table 2 Odds ratio (OR) and 95% confidence interval (CI) between 25(OH)D levels and breast cancer risk, CPS II Nutrition Cohort women
Quintiles of serum 25(OH)D concentration (nmol/L) | Pfor trend‡ | |||||
|---|---|---|---|---|---|---|
<36.7 | 36.7-<49.8 | 49.8-<60.8 | 60.8-<73.2 | 73.2+ | ||
All cases (n) | 89 | 115 | 99 | 118 | 95 | |
Controls (n) | 104 | 102 | 105 | 102 | 103 | |
OR (95% CI)* | 1.00 (-) | 1.31 (0.88-1.94) | 1.11 (0.74-1.66) | 1.35 (0.91-2.01) | 1.07 (0.71-1.61) | 0.8 |
OR (95%CI)† | 1.00 (-) | 1.29 (0.86-1.94) | 1.14 (0.75-1.72) | 1.44 (0.96-2.18) | 1.09 (0.70-1.68) | 0.6 |
Tertiles of serum 25(OH)D concentration (nmol/L) | P for trend ‡ | |||||
<45.9 | 45.9-<64.2 | 64.2+ | ||||
ER+ cases (n) | 102 | 120 | 120 | |||
Controls (n) | 177 | 160 | 179 | |||
OR (95% CI)* | 1.00 (-) | 1.32 (0.94-1.87) | 1.16 (0.82-1.63) | 0.4 | ||
OR (95%CI)† | 1.00 (-) | 1.32 (0.93-1.88) | 1.15 (0.80-1.65) | 0.5 | ||
ER- cases (n) | 17 | 16 | 16 | |||
Controls (n) | 177 | 160 | 179 | |||
OR (95% CI)* | 1.00 (-) | 1.02 (0.49-2.12) | 0.90 (0.44-1.87) | 0.8 | ||
OR (95%CI)† | 1.00 (-) | 1.03 (0.48-2.19) | 0.95 (0.43-2.06) | 0.9 | ||
In situ cases (n) § | 34 | 39 | 30 | |||
Controls (n) | 177 | 160 | 179 | |||
OR (95% CI)* | 1.00 (-) | 1.29 (0.77-2.16) | 0.89 (0.52-1.54) | 0.7 | ||
OR (95%CI)† | 1.00 (-) | 1.23 (0.72-2.09) | 0.87 (0.49-1.55) | 0.7 | ||
Localized cases (n) § | 90 | 114 | 114 | |||
Controls (n) | 177 | 160 | 179 | |||
OR (95% CI)* | 1.00 (-) | 1.44 (1.01-2.06) | 1.25 (0.88-1.79) | 0.2 | ||
OR (95%CI)† | 1.00 (-) | 1.45 (1.01-2.09) | 1.30 (0.90-1.89) | 0.2 | ||
Regional/Distant Cases (n) § | 35 | 25 | 28 | |||
Controls (n) | 177 | 160 | 179 | |||
OR (95% CI)* | 1.00 (-) | 0.79 (0.45-1.38) | 0.79 (0.46-1.37) | 0.4 | ||
OR (95%CI)† | 1.00 (-) | 0.78 (0.43-1.41) | 0.75 (0.41-1.37) | 0.3 | ||